Juan Ignacio Garcia 1,2,13, Holden V. Kelley3,13, Johanna Meléndez4, Rosa Alejandra Alvarez de León5, Alejandra Castillo6, Sabeen Sidiki7, Kizil A. Yusoof3, Elizabete Nunes8, Cesar López Téllez6, Carlos Rodolfo Mejía-Villatoro4,14, Janet Ikeda9, Alberto L. Garcia-Basteiro2,10,11, Shu-Hua Wang12 & Jordi B. Torrelles2* … Read more
Author Archives: cfriese
Hippocampal Stem Cells Promotes Synaptic Resistance To The Dysfunctional Impact Of Amyloid Beta Oligomers Via Secreted Exosomes.
Abbreviated Title: NSC-Mediated Synaptic Resistance To Ab Oligomers ABSTRACT Background Adult hippocampal neurogenesis plays an important role in supporting synaptic plasticity and cogntive function. We have recently reported that the presence of higher numbers of neural stem cells (NSC) in … Read more
An autophagy-inducing and TLR-2 activating BCG vaccine induces a robust protection against tuberculosis in mice
Abstract: Mycobacterium bovis BCG is widely used as a vaccine against tuberculosis due to M. tuberculosis (Mtb), which kills millions of people each year. BCG variably protects children, but not adults against tuberculosis. BCG evades phagosome maturation, autophagy, and reduces … Read more
High-throughput determination of the antigen specificities of T cell receptors in single cells
Abstract: We present tetramer-associated T-cell receptor sequencing (TetTCR-seq) to link T cell receptor (TCR) sequences to their cognate antigens in single cells at high throughput. Binding is determined using a library of DNA-barcoded antigen tetramers that is rapidly generated by in vitro transcription and translation. We … Read more
Kleberg Foundation awards UTRGV School of Medicine four-year grant for scholarships
RIO GRANDE VALLEY, TEXAS – JULY 25, 2019 – The Robert J. Kleberg, Jr. and Helen C. Kleberg Foundation has awarded The UTRGV School of Medicine a four-year, $2.5 million grant for scholarships for medical students from the Rio Grande Valley. The School … Read more
Zika Virus Vaccine: Progress and Challenges
Abstract The explosive emergence of Zika virus has inspired a global effort to develop vaccines. Zika virus, which is a flavivirus primarily transmitted by mosquitoes, can cause devastating congenital syndrome in fetuses of pregnant women, including microcephaly, craniofacial disproportion, spasticity, … Read more
Organ bioprinting gets a breath of fresh air
HOUSTON — (May 2, 2019) — Bioengineers have cleared a major hurdle on the path to 3D printing replacement organs with a breakthrough technique for bioprinting tissues. The new innovation allows scientists to create exquisitely entangled vascular networks that mimic … Read more
Kleberg Foundation gift furthers brain cancer research
By Sharon Reynolds CenterTimes, Summer 2018 For over half a century, the Robert J. Kleberg, Jr. and Helen C. Kleberg Foundation has improved the world, thanks to a deep passion for discovery, the earth, and the people surrounding them. The … Read more
Shriners: Bracing for the Future
TMC Pulse, March 09, 2018 By Shanley Chien On Dec. 8, 2017, Jesus Badillo Garcia and his mother, Patty Garcia, curled up in a 10-seat van parked outside a nondescript brick building off Interstate 2 in La Feria, Texas, a … Read more
Miller awarded Kleberg Foundation Medical Research Grant to advance lung tissue engineering
By Shawn Hutchins Rice BIOE News Rice University bioengineer Jordan Miller develops novel biomaterials and 3D bioprinting systems for next-generation tissue engineering applications. These technologies aim to build living tissue architectures that can closely mimic features of native vascular networks … Read more
