The oncoprotein transcription factor MYC is overexpressed in the majority of cancers. Key to its oncogenic activity is the ability of MYC to regulate gene expression patterns that drive and maintain the malignant state. MYC is also considered a validated … Read more
News Releases
Identifying allelopathic native plants for use in thorn forest restoration
Emily A Mullins, Graduate Student Oral Presentation Authors: Mullins, E., Fierro Cabo, A Affiliation University of Texas Rio Grande Valley The Tamaulipan thorn-forest is composed of species well adapted to semi-arid environments and is one of the most biodiverse regions … Read more
High density planting: positive interactions in thornforest restoration
Edgar Damian Vasquez, Graduate Student Oral Presentation Authors: Vasquez, E., Fierro-Cabo, A. Affiliation University of Texas Rio Grande Valley Natural habitats in the Rio Grande valley (RGV) have been degraded and lost through the conversion of thornscrub and other habitats … Read more
Invasive African grasses in south Texas: are they allelopathic?
Romeo G. Segura, Undergraduate Student Poster presentation Authors: Fierro-Caba A., Mullins E., Segura R. Affiliation School of Earth, Environmental, and Marine Sciences and Department of Biology. University of Texas Rio Grande Valley Megathyrsus maximus (Guinea grass), Dichanthium annulatum (Kleberg bluestem) … Read more
A simulation-based approach to improve decoded neurofeedback performance
Ethan F. Oblak a,*, James S. Sulzer a,1, Jarrod A. Lewis-Peacock b,1 The neural correlates of specific brain functions such as visual orientation tuning and individual finger movements can be revealed using multivoxel pattern analysis (MVPA) of fMRI data. Neurofeedback … Read more
High-throughput determination of the antigen specificities of T cell receptors in single cells
Shu-Qi Zhang1,7, Ke-Yue Ma2,7, Alexandra A Schonnesen3,7, Mingliang Zhang4,5,7, Chenfeng He3, Eric Sun3, Chad M Williams3, Weiping Jia4,5 & Ning Jiang2,3,6 We present tetramer-associated T-cell receptor sequencing (TetTCR-seq) to link T cell receptor (TCR) sequences to their cognate antigens in … Read more
Improved Alere Determine Lipoarabinomannan Antigen Detection Test for the Diagnosis of Human and Bovine Tuberculosis by Manipulating Urine and Milk
Juan Ignacio Garcia 1,2,13, Holden V. Kelley3,13, Johanna Meléndez4, Rosa Alejandra Alvarez de León5, Alejandra Castillo6, Sabeen Sidiki7, Kizil A. Yusoof3, Elizabete Nunes8, Cesar López Téllez6, Carlos Rodolfo Mejía-Villatoro4,14, Janet Ikeda9, Alberto L. Garcia-Basteiro2,10,11, Shu-Hua Wang12 & Jordi B. Torrelles2* … Read more
Hippocampal Stem Cells Promotes Synaptic Resistance To The Dysfunctional Impact Of Amyloid Beta Oligomers Via Secreted Exosomes.
Abbreviated Title: NSC-Mediated Synaptic Resistance To Ab Oligomers ABSTRACT Background Adult hippocampal neurogenesis plays an important role in supporting synaptic plasticity and cogntive function. We have recently reported that the presence of higher numbers of neural stem cells (NSC) in … Read more
An autophagy-inducing and TLR-2 activating BCG vaccine induces a robust protection against tuberculosis in mice
Abstract: Mycobacterium bovis BCG is widely used as a vaccine against tuberculosis due to M. tuberculosis (Mtb), which kills millions of people each year. BCG variably protects children, but not adults against tuberculosis. BCG evades phagosome maturation, autophagy, and reduces … Read more
High-throughput determination of the antigen specificities of T cell receptors in single cells
Abstract: We present tetramer-associated T-cell receptor sequencing (TetTCR-seq) to link T cell receptor (TCR) sequences to their cognate antigens in single cells at high throughput. Binding is determined using a library of DNA-barcoded antigen tetramers that is rapidly generated by in vitro transcription and translation. We … Read more
