News Releases

An archive of our media and press documents.

Single-cell multiomic comparison of mouse and rat spermatogenesis reveals gene regulatory networks conserved for over 20 million years

Summary Spermatogenesis is driven by dramatic changes in chromatin regulation, gene transcription, and protein expression.…

Thomas Jefferson University Receives $1.25M Grant to Tackle Bone Destruction in Metastatic Breast Cancer

Grant from the Robert J. Kleberg, Jr. and Helen C. Kleberg Foundation aims to develop…

Engineered PsCas9 enables therapeutic genome editing in mouse liver with lipid nanoparticles

Clinical implementation of therapeutic genome editing relies on efficient in vivo delivery and the safety…

Foundation funds research to block drug resistance in cancer treatment

The Robert J. Kleberg, Jr. and Helen C. Kleberg Foundation has funded an ambitious initiative…

A naturally occurring alternative to antibiotics? San Antonio Medical Foundation-funded research provides key assistance.

Phages, which live in the digestive tract, could treat bacterial infections if issues impacting effectiveness…

A Polarity-Sensitive Far-Red Fluorescent Probe for Glucose Sensing through Skin

Lydia Colvin, Dandan Tu, Darin Dunlap, Alberto Rios, and Gerard Coté  Abstract The field of glucose biosensors for diabetes management…

RNA targeting unleashes indiscriminate nuclease activity of CRISPR–Cas12a2

Abstract Cas12a2 is a CRISPR-associated nuclease that performs RNA-guided, sequence-nonspecific degradation of single-stranded RNA, single-stranded…

Evidence for reduced BRCA2 functional activity in Homo sapiens after divergence from the chimpanzee-human last common ancestor

Link to article https://www.cell.com/cell-reports/pdfExtended/S2211-1247(22)00535-6 Memorial Sloan Kettering Statement BRCA mutations have been implicated in pancreatic…

Reestablishment of spermatogenesis after more than 20 years of cryopreservation of rat spermatogonial stem cells reveals an important impact in differentiation capacity

Abstract Treatment of cancer in children is increasingly successful but leaves many prepubertal boys suffering…

Structural basis for mismatch surveillance by CRISPR–Cas9

Abstract CRISPR–Cas9 as a programmable genome editing tool is hindered by off-target DNA cleavage1,2,3,4, and…