News Releases

Reestablishment of spermatogenesis after more than 20 years of cryopreservation of rat spermatogonial stem cells reveals an important impact in differentiation capacity

Abstract Treatment of cancer in children is increasingly successful but leaves many prepubertal boys suffering…

Structural basis for mismatch surveillance by CRISPR–Cas9

Abstract CRISPR–Cas9 as a programmable genome editing tool is hindered by off-target DNA cleavage1,2,3,4, and…

Biogenic metallic elements in the human brain?

Abstract The chemistry of copper and iron plays a critical role in normal brain function.…

Roles of Stra8 and Tcerg1l in retinoic acid induced spermatogonial differentiation in mouse

Sinha, Whelan, Tobias, Avarbock, Stefanovski, Brinster. Biology of Reproduction, Volume 105, Issue 2, August 2021,…

Identification of vaccine targets in pathogens and design of a vaccine using computational approaches

Nature Scientific Reports | (2021) 11:17626 Kamal Rawal, Robin Sinha, Bilal Ahmed Abbasi, Amit Chaudhary,…

Zika virus oncolytic activity requires CD8+ T cells and is boosted by immune checkpoint blockade

Sharmila Nair,1 Luciano Mazzoccoli,1 Arijita Jash,1 Jennifer Govero,1 Sachendra S. Bais,1 Tong Hu,1 Camila R. Fontes-Garfias,2 Chao Shan,2 Hideho Okada,3,4 Sujan Shresta,5 Jeremy N. Rich,6,7,8 Pei-Yong…

Biogenic metallic elements in the human brain?

James Everett, Frederik Lermyte, Jake Brooks, Vindy Tjendana-Tjhin, Germán Plascencia-Villa, Ian Hands-Portman, Jane M. Donnelly,…

Thymic development of gut-microbiota-specific T cells

Abstract Humans and their microbiota have coevolved a mutually beneficial relationship, with the human host…

NF1 mutation drives neuronal activity-dependent initiation of optic glioma

Nature, published online: 26 May 2021 Neurons have recently emerged as essential cellular constituents of…

Biomimetic nano drug delivery carriers for treating cardiovascular diseases

Key Points •  Why do we need biomimicry? Which challenges does it aim to overcome?…