Medical Research

The Foundation is seeking highly innovative and groundbreaking medical research proposals from top tier institutions in both basic biological and applied research that will have the greatest impact on scientific knowledge and human health. Proposals should be distinctive and novel in their approaches, question the prevailing paradigm, and lead to advancement of knowledge in the field. A highly qualified scientific advisory committee will review all proposals.

Applications must be approved by the University Provost, or the Vice President of Research, and should be submitted through the office of research and sponsored projects, development department, or other office that provides institutional approval of the request. Applications submitted by an individual researcher will not be accepted. Applications are highly competitive. Priority is given to organizations with whom the Foundation has had a long-standing relationship.

Medical research institutions may submit a medical research application, regardless if they have an open grant, and regardless of the number of affiliated entities within the institution. There is a separate application for medical proposals with a format similar to that of NIH.

Before you begin your application, we request you contact Foundation staff at 210-271-3691 for guidance and eligibility, and also review the grant guidelines and the PDF documents below to be sure to submit a complete application:

2018 Medical Research Awards

Organization Name Amount
Johns Hopkins University, Baltimore, MD
Targeting Mitophagy as a New Strategy to Treat Non-Alcoholic Steatohepatitis
Texas A&M Foundation, College Station, TX
Innovative Technologies to Minimize the Risk for the Re-Emergence of Bovine Babesiosis in the U.S.
(Includes Contingency Award for Years 2 and 3)
University of California, San Francisco, CA
Early Detection and Removal of High-Risk Pre-Cancer, Cancer and Metastatic Lesions Using Engineered
Immune Cells
University of Pennsylvania, Philadelphia, PA
Epigenetic Dysfunction in Human Alzheimer’s Disease
University of Texas, Austin, TX
Improving the Efficiency and Specificity of Cas9 Enzymes

2017 Medical Research Awards

Organization Name Amount
Baylor College of Medicine, Houston, TX
Impact of Microbiota Driven T Cell Selection on Inflammatory Disease
Fred Hutchinson Cancer Research Center, Seattle, WA
Infusion of Off the Shelf Ex Vivo Expanded Cryopreserved Progenitor Cells for Single Cord Blood
Transplant in Patients with Hematologic Malignancies
Houston Methodist Hospital Foundation, Houston, TX
New Mechanisms and Strategies in Prevention of Transplant Rejection
A New Biomimetic Approach in the Treatment of Cardiovascular Inflammation
Memorial Hermann Foundation, Houston, TX
Plasma Exchange to Treat Alzheimer’s Disease
Memorial Sloan Kettering Cancer Center, New York, NY
Mechanistic Analyses of Pancreatic Cancer Evolution
Rice University, Houston, TX
Design and Fabrication of Interpenetrating Vascular Networks in Lung Tissue Mimics
Texas A&M Foundation, College Station, TX
Transformative and Affordable Medical Technologies and Systems to Improve Diabetes Health
Texas Children’s Hospital, Houston, TX
Network Systems Biology to Identify and Test Novel Multivalent mRNA Lipopolyplex Vaccines
Against Chagas Disease
Texas Heart Institute, Houston, TX
Targeting the Cardiovascular Inflammatory Receptor to Enhance Stem Cell Transplantation in Cancer
University of Houston, Houston, TX
Gravin Signalosome: A Novel Therapeutic Drug Target for the Treatment of Heart Failure
University of Texas at Austin, Austin, TX
A Personalized Approach to T Cell Receptor Re-Directed Adoptive Cell Transfer Therapy in Cancer
University of Texas at San Antonio, San Antonio, TX
Accelerating Research in Brain Health
University of Texas Medical Branch, Galveston, TX
A Rapid Zika Diagnostic Assay for Patients
Innovative Methods to Disrupt Acquisition and Transmission of Viruses by Mosquitoes and Ticks
UT Southwestern Medical Center, Dallas, TX
Matching IDH Driver Status toTreatment Timing in Glioma
Vanderbilt University Medical Center, Nashville, TN
Accelerating the Transition from Discovery to Clinical Implementation in Precision Medicine
Washington University, St. Louis, MO
Using Zika Virus to Treat Glioblastoma