Abstract The chemistry of copper and iron plays a critical role in normal brain function. A variety of enzymes and proteins containing positively charged Cu+, Cu2+, Fe2+, and Fe3+ control key processes, catalyzing oxidative metabolism and neurotransmitter and neuropeptide production. Here, … Read more →

AUTHORS:  Suchi Raghunathan1, Jose Francisco Islas2, Brandon Mistretta3, Dinakar Iyer3, Liheng Shi4, Preethi H. Gunaratne3, Gladys Ko4, Robert J. Schwartz3*, and Bradley K. McConnell (co-senior author)1* AFFILIATIONS:  1 Department of Pharmacological and Pharmaceutical Sciences, College of Pharmacy, University of Houston, Houston, TX 77204-5037, … Read more →

Abstract The explosive emergence of Zika virus has inspired a global effort to develop vaccines. Zika virus, which is a flavivirus primarily transmitted by mosquitoes, can cause devastating congenital syndrome in fetuses of pregnant women, including microcephaly, craniofacial disproportion, spasticity, … Read more →